yģö@{āV E@Shinobu Honzawa
1971N9ķ
m(ōw)(kåw)
TEL : 0250-25-5242@FAX : 0250-25-5298
e-mail : honzawa@nupals.ac.jp
wð
1994N |
åwōwŧōŧwČ@ēÆ |
1996N |
åwåw@ōwnĪČCmÛö@Cđ |
1999N |
åwåw@ōwnĪČmÛö@rÞw |
Eð
1999N`2003N |
kåwōw@č |
2003N`2006N |
éåwōw@č |
2006N` |
VōČåwōw@ģö |
wp_ķ
S. Honzawa, N. Takahashi, A. Yamashita, T. Sugiura, M. Kurihara, M. A. Arai, S.
Kato, A. Kittaka.
"Synthesis of a 1ŋ-C-Methyl Analogue of 25-Hydroxyvitamin D3:
Interaction with a Mutant Vitamin D Receptor Arg274Leu"
Tetrahedron 2009, 65, 7153-7145.
S. Honzawa, Y. Yamamoto, A. Yamashita, T. Sugiura, M. Kurihara, M. A. Arai, S.
Kato, A. Kittaka.
"The 2ŋ-(3-Hydroxypropyl) Group as an Active Motif in Vitamin D3
Analogues as Agonists of the Mutant Vitamin D Receptor (Arg274Leu)"
Bioorg. Med. Chem. 2008, 16, 3002-3024.
N. Saito, S. Honzawa, A. Kittaka.
"Recent Results on A-Ring Modification of 1ŋ,25-Dihydroxyvitamin D3:
Design and Synthesis of VDR-Agonists and Antagonists with High Biological
Activity"
Curr. Top. Med. Chem. 2006, 6, 1273-1288.
S. Honzawa, K. Hirasaka, Y. Yamamoto, S. Peleg, T. Fujishima, M. Kurihara, N.
Saito, S. Kishimoto, T. Sugiura, K. Waku, H. Takayama, A. Kittaka.
"Design, Synthesis and Biological Evaluation of Novel 1ŋ ,25-Dihydroxyvitamin D3
Analogues Possessing Aromatic Ring on 2ŋ-Position"
Tetrahedron, 2005, 61, 11253-11263.
S. Honzawa, Y. Yamamoto, K. Hirasaka, H. Takayama and A. Kittaka
"Synthesis of A-ring Synthon of 2ŋ-Substituted Vitamin D3 Analogues
Utilizing Grignard Reaction towards Methyl
2,3-Anhydro-4,6-O-benzylidene-ŋ-D-mannopyranoside"
Heterocycles, 2003, 61, 327-338.
S. Honzawa, Y. Suhara, K. Nihei, N. Saito, S. Kishimoto, T. Fujishima, M.
Kurihara, T. Sugiura, K. Waku, H. Takayama and A. Kittaka
"Concise Synthesis and Biological Activities of 2ŋ-Alkyl- and
2ŋ-(Ö-Hydroxyalkyl)-20-epi-1ŋ,25-dihydroxyvitamin D3"
Bioorg. Med. Chem. Lett., 2003, 13, 3503-3506.
T. Mizutani, S. Honzawa, S. Tosaki and M. Shibasaki
"Total Synthesis of (})-Wortmannin"
Angew. Chem. Int. Ed., 2002, 41, 4680-4682.
S. Honzawa, H. Okubo, S. Anzai, M. Yamaguchi, K. Tsumoto and I. Kumagai
"Chiral Recognition in the Binding of Helicene and Double Strand DNA:
Interaction Between Low Molecular Weight Helical Compounds and a Helical
Polymer"
Bioorg. Med. Chem., 2002, 10, 3213-3218.
S. Honzawa, H. Okubo, K. Nakamura, S. Anzai, M. Yamaguchi and C. Kabuto
"Folding of Dihelicenetriamines in Water"
Tetrahedron: Asymmetry, 2002, 13, 1043-1052.
S. Honzawa, S. Chiba, H. Okubo and M. Yamaguchi
"One-step Synthesis of Optically Active Cyclic Polyamines Containing Helicene"
Heterocycles, 2002, 57, 1091-1099.
S. Honzawa, S. Ohwada, Y. Morishita, K. Sato, N. Katagiri and M. Yamaguchi
"Synthesis and Hybridization Property of Oligonucleotides Containing Carbocyclic
Oxetanocins"
Tetrahedron, 2000, 56, 2615-2627.
〒956-8603 VsHtæ265-1VōČåwōwōŧwģš@TEL & FAX : 0250-25-5241
e-mail : taku@nupals.ac.jp@URL : http://www.taku-lab.com/